Mars Sample Receiving Facility and sample containment: Difference between revisions

no edit summary
No edit summary
Line 27:
</ref> .
 
The NRC and ESF findings on risks of [[Environmental degradation|environmental disruption]] are accepted by most participants in this debate (with the notable exception of Robert Zubrin<ref name=zubrin>Robert Zubrin "Contamination From Mars: No Threat", [http://www.planetary.org/explore/the-planetary-report/ The Planetary Report] July/Aug. 2000, P.4–5</ref><ref name=zubrin-interview>[http://astronomy.nmsu.edu/cwc/Teaching/SpaceCol/sts497i/Zubrin/transcript.txt transcription of a tele-conference interview with ROBERT ZUBRIN] conducted on March 30, 2001 by the class members of STS497 I, "Space Colonization"; Instructor: Dr. Chris Churchill</ref>). As a result, it is agreed by most researchers that a full and open public debate of the back contamination issues is needed at an international level.<!--(NASA and ESF surveys both say this as well as other sources e.g.) --><ref name=esf2012_PP-debate>{{cite report |title=Mars Sample Return backward contamination - strategic advice |publisher= European Science Foundation |year=2012 |chapter=5: "The Potential for Large-Scale Effects"|url=httphttps://web.archive.org/web/20130306111453/https://science.nasa.gov/media/medialibrary/2013/01/17/ESF_Mars_Sample_Return_backward_contamination_study.pdf|quote=''RECOMMENDATION 10: Considering the global nature of the issue, consequences resulting from an unintended release could be borne by a larger set of countries than those involved in the programme. It is recommended that mechanisms dedicated to ethical and social issues of the risks and benefits raised by an MSR are set up at the international level and are open to representatives of all countries.''}}</ref> This is also a legal requirement.<ref name=esf2010_RALOS>[httphttps://web.archive.org/web/20130306111453/https://science.nasa.gov/media/medialibrary/2013/01/17/ESF_Mars_Sample_Return_backward_contamination_study.pdf Mars Sample Return backward contamination – Strategic advice and requirements] see 7.2: Responsibility and liability of States</ref><ref name=race>M. S. Race [http://salegos-scar.montana.edu/docs/Planetary%20Protection/AdvSpaceResVol18(1-2).pdf Planetary Protection, Legal Ambiguity, and the Decision Making Process for Mars Sample Return] Adv. Space Res. vol 18 no 1/2 pp (1/2)345-(1/2)350 1996</ref>
 
Because of these concerns, there are proposals to build a Mars Sample Receiving Facility. This needs to be of a novel design, as it has to function both as a clean room and as a biohazard laboratory
Line 52:
 
The view in the reports from the National Research Council<ref name=nrc2009>
{{cite report |title=Assessment of Planetary Protection Requirements for Mars Sample Return Missions |publisher=National Research Council |year=2009 |chapter=2: "The Potential for Past or Present Habitable Environments on Mars" | url=http://www.nap.edu/openbook.php?record_id=12576&page=22}}</ref> and the European Science Foundation,<ref name=esf2012_PP>[httphttps://web.archive.org/web/20130306111453/https://science.nasa.gov/media/medialibrary/2013/01/17/ESF_Mars_Sample_Return_backward_contamination_study.pdf European Science Foundation - Mars Sample Return backward contamination - strategic advice] July, 2012, {{ISBN|978-2-918428-67-1}}. (for more details of the document see [http://elib.dlr.de/78092/ abstract] )</ref><ref name=Hsu>Jeremy Hsu [http://www.astrobio.net/exclusive/3329/keeping-mars-contained Keeping Mars Contained (illustrated with the FLAD, DC and LAS Mars Receiving Facility designs] Astrobiology Magazine, 12/03/09</ref> as well as the Planetary Protection office<ref name=ppo_msr_risk>
{{cite report |title=Mars Sample Return: Issues and Recommendations (Planetary Protection Office Summary) |publisher=Planetary Protection Office |year=1997|url=http://planetaryprotection.nasa.gov/summary/msr|quote=''The potential for large-scale effects, either through pathogenesis or [[Environmental degradation|ecological disruption]], is extremely small. Thus, the risks associated with inadvertent introduction of exogenous microbes into the terrestrial environment are judged to be low. However, any assessment of the potential for harmful effects involves many uncertainties, and the risk is not zero. ... The SSB task group strongly endorses NASA’s Exobiological Strategy for Mars Exploration (NASA, 1995). Such an exploration program, while likely to greatly enhance our understanding of Mars and its potential for harboring life, nonetheless is not likely to significantly reduce uncertainty as to whether any particular returned sample might include a viable exogenous biological entity-at least not to the extent that planetary protection measures could be relaxed.''}}</ref> is as follows:
 
Line 159:
=== ESF update on biohazard risks of MSR ===
 
The ESF report<ref name=esf2012_PP/> accepts the general conclusions of the NRC report, but went beyond them in several areas. In particular they made a more detailed assessment of size limits of micro-organisms. Before this study, the accepted size limits <ref name=esf2010_3size>[httphttps://web.archive.org/web/20130306111453/https://science.nasa.gov/media/medialibrary/2013/01/17/ESF_Mars_Sample_Return_backward_contamination_study.pdf Mars Sample Return backward contamination – Strategic advice and requirements] see 3. Life as we know it and size limits</ref> were 0.25&nbsp;µm, derived from a 1999 workshop.<ref name=size1999>[http://www.nap.edu/openbook.php?record_id=9638&page=2 Size Limits of Very Small Microorganisms: Proceedings of a Workshop] ( 1999 ) see Page 2 for the quote, "Given the uncertainties inherent in this estimate the panel agreed that 250 ± 50 nm as a reasonable lower limit for life as we know it"</ref>
 
The 2010 ESF study observed that the Mars sample could contain [[Archaea#Species|uncultivatable archaea]], or [[ultramicrobacteria]]. It might contain Martian [[Nanobacterium|nanobacteria]] 0.1&nbsp;µm if such exist. A recent concern is that it could contain virus-types and genetransfer agents as small as 0.03&nbsp;µm in size, especially if Mars life and Earth life share a common ancestor at some point.<ref name=esf2010_LAWKI>[httphttps://web.archive.org/web/20130306111453/https://science.nasa.gov/media/medialibrary/2013/01/17/ESF_Mars_Sample_Return_backward_contamination_study.pdf European Science Foundation - Mars Sample Return backward contamination - strategic advice] - (see Life as we know it and size limits) - February 23, 2010</ref> It might also contain forms of life that don't exist on Earth, possibly based on novel life chemistry, which makes it hard to set an absolute lower size.
 
For the nanobacteria, they accepted recent research that show these 0.1&nbsp;µm sized cell like objects are mineral deposits, so ruled them out. They discussed [[ultramicrobacteria]] and concluded that the smallest free-living self-replicating microorganisms observed are in the range of 0.12–0.2&nbsp;µm.
Line 206:
==Risk Mitigation for back contamination==
 
[[NASA]] has addressed back contamination concerns with a proposal to build a special biohazard containment facility to receive the samples, and with a sample return mission designed to break the chain of contact with Mars for the exterior of the sample container<ref name=esf2010_PP>[httphttps://web.archive.org/web/20130306111453/https://science.nasa.gov/media/medialibrary/2013/01/17/ESF_Mars_Sample_Return_backward_contamination_study.pdf European Science Foundation - Mars Sample Return backward contamination - strategic advice] February 23, 2010, {{ISBN|978-2-918428-67-1}} - see Back Planetary Protection section. (for more details of the document see [http://elib.dlr.de/78092/ abstract] )</ref><ref>Jeremy Hsu [http://www.astrobio.net/exclusive/3329/keeping-mars-contained Keeping Mars Contained] Astrobiology Magazine, 12/03/09</ref>
 
In the European Science Foundation study, these risks were studied in more detail and recommendations made to reduce them to levels considered acceptable.
Line 259:
To deal with issues of the novelty of the facilities and of human error, the studies recommended that the receiving facility is operational and the staff trained several years before the Mars samples are brought into Earth's environment. The 2008 report of the IMARS working group report detailed a total of twelve years from initial planning to lander launch.<ref name=imars>[http://mepag.nasa.gov/reports/iMARS_FinalReport.pdf Preliminary Planning for an International Mars Sample Return Mission] Report of the International Mars Architecture for the Return of Samples (iMARS) Working Group, June 1, 2008</ref> Three architectural firms were approached who provided preliminary plans, the FLAD, IDC and LAS plans, the last of these, the LAS has a fully robotic work force to handle the samples.<ref>Jeremy Hsu [http://www.astrobio.net/exclusive/3329/keeping-mars-contained Keeping Mars Contained] Astrobiology Magazine 12/03/09</ref><ref>Beaty DW, Allen CC, Bass DS, Buxbaum KL, Campbell JK, Lindstrom DJ, Miller SL, Papanastassiou DA. [http://www.ncbi.nlm.nih.gov/pubmed/19845446?report=abstract Planning considerations for a Mars Sample Receiving Facility: summary and interpretation of three design studies.] Astrobiology. 2009 Oct;9(8):745-58. doi: 10.1089/ast.2009.0339.</ref><ref>[http://www.nap.edu/openbook.php?record_id=5563&page=31 Mars Sample Return: Issues and Recommendations](1997)] Task Group on Issues in Sample Return, National Research Council (page 31)</ref>
 
They were not asked to consider human factors and so do not report on ways to mitigate these, except to suggest that care must be taken to minimize human interaction with the sample.<ref name=esf2012_PP-human-factors>{{cite report |title=Mars Sample Return backward contamination - strategic advice |publisher= European Science Foundation |year=2012 |chapter=4.7 Potential verification methods"|url=httphttps://web.archive.org/web/20130306111453/https://science.nasa.gov/media/medialibrary/2013/01/17/ESF_Mars_Sample_Return_backward_contamination_study.pdf |quote=''While the Study Group was not tasked with considering human factors, it has to be highlighted that the use of human handling in this process and the transport itself entails the risk of human error and the potential for accidental release. For this reason, care must be taken to minimise human interaction with the sample and to provide adequate protection via transport containment to guard against an accident during transport to the curation facility.''}}</ref>
 
===Concerns about incubation period===
Line 269:
The WHO Leprosy fact sheet<ref>[http://www.who.int/mediacentre/factsheets/fs101/en/ Leprosy Fact Sheet] World Health Organization</ref> gives the [[incubation period]] of [[leprosy]], from first infection to onset of symptoms, as up to 20 years.
 
In the European Science Foundation report, incubation period is listed as the first of the list of unknowns that make it impossible to use standard models for the effects of a release and its consequences <ref name=esf2012_PP-precautionary>[httphttps://web.archive.org/web/20130306111453/https://science.nasa.gov/media/medialibrary/2013/01/17/ESF_Mars_Sample_Return_backward_contamination_study.pdf European Science Foundation - Mars Sample Return backward contamination - strategic advice] - (see 5.3 Direct consequences for human health) - July, 2012</ref>
 
====Risk mitigation for incubation period====
Line 306:
They recommend that potential release scenarios (including undetected release) are clearly defined and investigated, and response strategies developed for them.
 
They considered it critical that such containment strategies are implemented as soon as possible at the local level, and that they should include rapid detection of anomalies, effective warning procedures, and analysis, resistance and mitigation procedures.<ref name=esf2012_PP-being-prepared>{{cite report |title=Mars Sample Return backward contamination - strategic advice |publisher= European Science Foundation |year=2012 |chapter=5: "The Potential for Large-Scale Effects - 5.4 Being prepared"|url=httphttps://web.archive.org/web/20130306111453/https://science.nasa.gov/media/medialibrary/2013/01/17/ESF_Mars_Sample_Return_backward_contamination_study.pdf |quote=''It is critical that such strategies are designed to be implemented as soon as possible and at the local level and that they encompass:<br>• observation of pre-defined indicators<br>• rapid detection of anomalies<br>• effective warning procedures<br>• analysis, resistance and mitigation procedures''}}</ref>
 
====Views of the 2002 COMPLEX study of lessons to be learnt from the Apollo quarantine====